Hypnotism, Hysteria and Epilepsy. An Historical Synthesis
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At present, herbal therapies are tried by patients in developing as well as developed countries for control of seizures or adverse effects from antiepileptic drugs, or for general health maintenance. There are number of synthetic drugs available for treatment of epilepsy in modern therapy, but the major disadvantage being faced is their chronic side effects.
Treatment of epilepsy with herbal drugs as adjuvant seems to be more beneficial and is gaining more popularity due to their fewer side effects. Users Online: Herbal and synthetic approaches for the treatment of epilepsy. Types of Epilepsy. Diagnosis and Treatment. Older Generation Drugs. Newer Antiepileptic Drugs.
Table 1: Common side effects of antiepileptic drugs Click here to view. Herbal Drugs Used in Treatment of Epilepsy. Table 2: Plants used in the treatment of Epilepsy Click here to view.
Table 3: Marketed formulation available in India Click here to view. Progress in neuroprotective strategies for preventing epilepsy. Prog Neurobiol ; Advancements in traditional medicinal plants used in epilepsy. Phcog Rev ; Neligan A, Sander JW. The incidence and prevalence of epilepsy UCL. Institute of Neurology, Queen Square: London. Epilepsy in the renaissance: A survey of remedies from 16 th and 17 th century German herbals. J Ethnopharmacol ; White Discovery of antiepileptic drugs. Neurotherapeutics ; Schachter SC. Currently available antiepileptic drugs.
Hypnotism, Hysteria and Epilepsy
Botanicals and herbs: A traditional approach to treating epilepsy. Available from: www. Patsalos PN, Perucca E. Clinically important drug interactions in epilepsy: Interactions between antiepileptic drugs and other drugs. Lancet Neurol ; Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum. Loscher W. New visions in the pharmacology of anticonvulsion. Eur J Pharmacol ; March PA.
Seizures: Classification, etiologies, and pathophysiology. Clin Tech Small Anim Pract ; Plants and plant products with potential anticonvulsant activity: A review pharmacognosy communications ;2 1, Suppliment. Vajda FJ. Pharmacotherapy of epilepsy: New armamentarium, new issues.
J Clin Neurosci ; Do carbamazepine and phenytoin aggravate juvenile myoclonic epilepsy? Neurology ; Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics. Willmore LJ. Epilepsy emergencies: The first seizure and status epilepticus. Neurology ;S Congenital malformations due to antiepileptic drugs. Epilepsy Res ; Crawford P. Interactions between antiepileptic drugs and hormonal contraception.
CNS Drugs ; Antiepileptic drug mechanisms of action. Epilepsia ;36 Suppl 2:S Perucca E. Pharmacological and therapeutic properties of valproate: A summary after 35 years of clinical experience. Venkataraman V, Wheless JW. Safety of rapid intravenous infusion of valproate loading doses in epilepsy patients. Phenylethylmalonamide PEMA. An important metabolite of primidone. Arch Neurol ; Seizures during barbiturate withdrawal: Relation to blood level. Ann Neurol ; Stefan H, Feuerstein TJ. Novel anticonvulsant drugs. Pharmacol Therap ; You can view this on the NLA website.
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